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Donanemab, sold under the brand name Kisunla, is a monoclonal antibody used for the treatment of Alzheimer's disease. [1] [2] Donanemab was developed by Eli Lilly and Company. [3] [4] The most common side effects include amyloid-related imaging abnormalities and headache. [2] Donanemab was approved for medical use in the United States in July 2024.
Evidence suggests that people get the most benefit if they are given the treatment earlier in the disease. Treatment with donanemab reduced amyloid plaque on average by 84% at 18 months, Lilly found.
In Lilly's large clinical trial, donanemab, given by infusion once a month, slowed progression of memory and thinking problems by 29% overall, roughly comparable to the 27% slowing seen with Leqembi.
Lilly's donanemab, administered via once-a-month infusions, is designed to clear a toxic Alzheimer's-linked protein called beta amyloid from the brain. ... Three people who were on the treatment ...
A cat eating grass – an example of zoopharmacognosy. Zoopharmacognosy is a behaviour in which non-human animals self-medicate by selecting and ingesting or topically applying plants, soils and insects with medicinal properties, to prevent or reduce the harmful effects of pathogens, toxins, and even other animals.
Glucosinolate structure; side group R varies. Glucosinolates are natural components of many pungent plants such as mustard, cabbage, and horseradish.The pungency of those plants is due to mustard oils produced from glucosinolates when the plant material is chewed, cut, or otherwise damaged.
The study, published in the Journal of the American Medical Association, concluded that after 76 weeks of treatment, Donanemab was able to slow clinical decline by 35.1% in people with early ...
The drug, donanemab, was developed by pharmaceutical company Eli Lilly and is marketed under the name Kinusla. It was approved on July 2 and is the third infusion-based drug to slow symptoms, said ...