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More than 75% of women with rheumatoid arthritis have symptoms improve during pregnancy but might have symptoms worsen after delivery. [20] Methotrexate and leflunomide are teratogenic (harmful to foetus) and not used in pregnancy. It is recommended women of childbearing age should use contraceptives to avoid pregnancy and to discontinue its ...
Women are twice as likely to get PMR as men. [27] White people of western and Northern European descent are more likely to get this disease. [2] It is more likely to affect people of Northern European origin; Scandinavians are especially vulnerable. [27] About 50% of people with temporal arteritis also have polymyalgia rheumatica. [2]
Palindromic rheumatism is a disease of unknown cause. It has been suggested that it is an abortive form of rheumatoid arthritis (RA), since anti-cyclic citrullinated peptide antibodies (anti-CCP) and antikeratin antibodies (AKA) are present in a high proportion of patients, as is the case in rheumatoid arthritis. [6]
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High levels of rheumatoid factor (in general, above 20 IU/mL, 1:40, or over the 95th percentile; there is some variation among labs) occur in rheumatoid arthritis (present in 80%) and Sjögren's syndrome (present in 50-70% of primary forms of disease). [11] The higher the level of RF the greater the probability of destructive articular disease.
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