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The stage of a lymphoma helps predict a patient's prognosis and is used to help select the appropriate therapy. [ 44 ] The Ann Arbor staging system is routinely used for staging of both HL and NHL.
The authors concluded that trials using a patient mix weighted toward good prognosis will not find such a difference. In 1993, a retrospective analysis was performed on 2031 patients with aggressive non-Hodgkin's lymphoma, of all ages, treated with a doxorubicin-based chemotherapy regimen such as CHOP between 1982 and 1987. [2]
Primary CNS lymphoma is highly associated with Epstein-Barr virus (EBV) infection (> 90%) in immunodeficient patients (such as those with AIDS and those immunosuppressed), [4] and does not have a predilection for any particular age group. Mean CD4+ count at time of diagnosis is ~50/μL. In immunocompromised patients, prognosis is usually poor.
Score X: New areas of uptake unlikely to be related to lymphoma; Scores of 1 and 2 are considered to be negative and 4 and 5 are considered to be positive. "Score 3 should be interpreted according to the clinical context but in many Hodgkin Lymphoma patients indicates a good prognosis with standard treatment." [2]
Prognosis is favourable in comparison with classic HL [20] despite a tendency for disease recurrence requiring long term followup. [15] [14] Relapse can occur at a comparatively late stage in comparison to classic HL. [14] There is limited information regarding the outcome for patients with advanced-stage progression. [14]
Diffuse large B-cell lymphoma (DLBCL) is a cancer of B cells, a type of lymphocyte that is responsible for producing antibodies.It is the most common form of non-Hodgkin lymphoma among adults, [1] with an annual incidence of 7–8 cases per 100,000 people per year in the US and UK.
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