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  2. Trazodone - Wikipedia

    en.wikipedia.org/wiki/Trazodone

    Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.

  3. List of radioactive nuclides by half-life - Wikipedia

    en.wikipedia.org/wiki/List_of_radioactive...

    This is a list of radioactive nuclides (sometimes also called isotopes), ordered by half-life from shortest to longest, in seconds, minutes, hours, days and years. Current methods make it difficult to measure half-lives between approximately 10 −19 and 10 −10 seconds. [1]

  4. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.

  5. Daridorexant - Wikipedia

    en.wikipedia.org/wiki/Daridorexant

    Its half-life is shorter than that of other orexin receptor antagonists such as suvorexant (12 hours) and lemborexant (~18–55 hours). [5] The relatively short half-life of daridorexant may allow for reduced daytime sedation. [5] [16] The duration of action of daridorexant in terms of sedative effects is approximately 8 hours with a 50 mg dose ...

  6. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    They showed that "In terms of efficacy, all antidepressants were more effective than placebo, with odds ratios (ORs) ranging between 2.13 (95% credible interval [CrI] 1.89–2.41) for amitriptyline and 1.37 (1.16–1.63) for reboxetine." [16] The odds ratios were specifically in terms of response rates (≥50% reduction in observer-rated ...

  7. Primidone - Wikipedia

    en.wikipedia.org/wiki/Primidone

    The usual dose range is 120 to 250 mg/day in two divided doses or as one single dose. ... trazodone 50 mg ... Phenobarbital reduces the half-life to 4.8 ± 1.3 and ...

  8. 100 micrograms of MM120 is classified as a single dose of the drug. Just that amount led to a 48% rate of remission from generalized anxiety disorder after 12 weeks, MindMed reported.

  9. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.

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