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[1] [7] The condition may cause chronic pain, such as a constant dull ache, which can be worsened by standing or sex. [1] Pain in the legs or lower back may also occur. [1] While the condition is believed to be due to blood flowing back into pelvic veins as a result of faulty valves in the veins, this hypothesis is not certain. [7]
Peripheral veinous disease, on the other hand, refers to problems with veins—the vessels that bring the blood back to the heart. [18] The classic symptom is leg pain when walking, which resolves with rest and is known as intermittent claudication. [2]
One study [2] found that infection was the cause of pain in four percent of nearly 300 cancer patients referred for pain relief. Another report [3] described seven patients, whose previously well-controlled pain escalated significantly over several days. Antibiotic treatment produced pain relief in all patients within three days. [4]
Signs and symptoms include low back pain, pain that radiates down the leg, numbness around the anus, and loss of bowel or bladder control. [1] Onset may be rapid or gradual. [1] The cause is usually a disc herniation in the lower region of the back. [1] Other causes include spinal stenosis, cancer, trauma, epidural abscess, and epidural hematoma.
Symptoms classically affect a leg and typically develop over hours or days, [20] though they can develop suddenly or over a matter of weeks. [21] The legs are primarily affected, with 4–10% of DVT occurring in the arms. [11] Despite the signs and symptoms being highly variable, [5] the typical symptoms are pain, swelling, and redness.
Rest pain is a continuous burning pain of the lower leg or feet. It begins, or is aggravated, after reclining or elevating the limb and is relieved by sitting or standing. It is more severe than intermittent claudication, which is also a pain in the legs from arterial insufficiency. [citation needed]
Dr. Narayanan says that bone pain can also be a sign of prostate cancer recurrence in patients who have already had the disease. The link between prostate cancer and bone pain may be a surprising one.
The predominant symptoms of NC involve one or both legs and usually presents as some combination of tingling, cramping discomfort, pain, numbness, or weakness in the lower back, calves, glutes, and thighs and is precipitated by walking and prolonged standing. However, the symptoms vary depending on the severity and cause of the condition.
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