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The mechanisms behind allergic asthma—i.e., asthma resulting from an immune response to inhaled allergens—are the best understood of the causal factors. In both people with asthma and people who are free of the disease, inhaled allergens that find their way to the inner airways are ingested by a type of cell known as antigen-presenting ...
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
Allergic inflammation is an important pathophysiological feature of several disabilities or medical conditions including allergic asthma, atopic dermatitis, allergic rhinitis and several ocular allergic diseases. Allergic reactions may generally be divided into two components; the early phase reaction, and the late phase reaction.
The Journal of Asthma and Allergy is a peer-reviewed medical journal focusing on asthma and pulmonary physiology. The journal was established in 2008 and is published by Dove Medical Press . External links
Acute severe asthma; Airway remodelling; Alcohol-induced respiratory reactions; Allergies in children; Anti-asthmatic agent; Aspirin-exacerbated respiratory disease; Asthma; Asthma and Allergy Friendly; Asthma Life Impact Scale; Asthma phenotyping and endotyping; Asthma trigger; Asthma-COPD overlap; Asthma-related microbes; Asthmagen
Sensitizer-induced occupational asthma is an immunologic form of asthma which occurs due to inhalation of specific substances (i.e., high-molecular-weight proteins from plants and animal origins, or low-molecular-weight agents that include chemicals, metals and wood dusts) and occurs after a latency period of several weeks to years. [1]
Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. [1] An asthma attack is characterized by an obstruction of the airway , hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the ...
Estimates of between 0.5 and 3.5% have been made for ABPA burden in asthma, [32] [33] and 1–17.7% in CF. [32] [34] Five national cohorts, detecting ABPA prevalence in asthma (based on GINA estimates), [35] were used in a recent meta-analysis to produce an estimate of the global burden of ABPA complicating asthma. From 193 million people with ...