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  2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

  3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Tadalafil side effects aren’t the only concern when taking this drug. As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications prescribed to treat hypertension ...

  4. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [ 5 ] [ 6 ] [ 8 ] It is taken by mouth . [ 8 ]

  5. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    What is Cialis (Tadalafil)? Like other ED medications, Cialis is a PDE5 inhibitor.It works by blocking the effects of PDE5, or cGMP-specific phosphodiesterase type 5 — an enzyme that’s ...

  6. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    The major PDE5 inhibitors (a subset of the phosphodiesterase inhibitors) are sildenafil, tadalafil, vardenafil, and avanafil, and although all share the same mechanism of action each has unique pharmacokinetic and pharmacodynamic properties which dictate their suitability in various conditions and their side effect profile. [3]

  7. cGMP-specific phosphodiesterase type 5 - Wikipedia

    en.wikipedia.org/wiki/CGMP-specific_phosphodi...

    Tadalafil (marketed as Cialis) is a PDE5 inhibitor used to treat erectile dysfunction [23] and pulmonary arterial hypertension. [24] It has a longer half life than sildenafil of 17.5 hours, allowing it to be taken once a day. [24] Tadalafil "daily" (5 mg) is also used for treatment of benign prostate hyperplasia. [25]

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