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A nicotine patch is a transdermal patch that releases nicotine into the body through the skin. It is used in nicotine replacement therapy (NRT), a process for smoking cessation . Endorsed and approved by the U.S. Food and Drug Administration (FDA), it is considered one of the safer NRTs available for the treatment of tobacco use disorder .
Nicotine is an agonist at nicotinic acetylcholine receptor which are present in the central and autonomic nervous systems, and the neuromuscular junction. At low doses nicotine causes stimulatory effects on these receptors, however, higher doses or more sustained exposures can cause inhibitory effects leading to neuromuscular blockade. [4] [30]
Nicotine replacement therapy is as effective as medications, such as bupropion, in helping people quit smoking for at least six months. [16] All forms of nicotine replacement therapy, including nicotine gum, patches, nasal spray, inhalers, and lozenges, have similar success rates in terms of helping people stop smoking.
This is an accepted version of this page This is the latest accepted revision, reviewed on 31 December 2024. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here ...
While acute/initial nicotine intake causes activation of neuronal nicotine receptors, chronic low doses of nicotine use leads to desensitization of those receptors (due to the development of tolerance) and results in an antidepressant effect, with early research showing low dose nicotine patches could be an effective treatment of major ...
While pipe smoking may seem less harmful than cigarettes or cigars, it still involves inhaling nicotine and harmful substances. Health risks include respiratory problems and cancers, particularly ...
Jarvik and Rose's research led to their invention of the nicotine patch in the early 1990s. [1] [2] The nicotine patch is a transdermal patch that delivers nicotine directly through the skin and into the body to alleviate the urge to smoke and, hopefully, ultimately quit smoking. [2]
While he mostly quit cold turkey, Richards, 78, also used "a few patches for a few weeks." But ultimately, he realized it was time to ditch the habit for good. "Sometimes, you know, a bell rings ...