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  2. Computerized system validation - Wikipedia

    en.wikipedia.org/wiki/Computerized_system_validation

    The system lifecycle then enters the operational phase and continues until system retirement and retention of system data based on regulatory rules. Similarly, The Rules Governing Medicinal Products in the European Union, Volume 4, Annex 11: Computerised Systems applies to all forms of computerized systems used as part of a GMP regulated ...

  3. Title 21 CFR Part 11 - Wikipedia

    en.wikipedia.org/wiki/Title_21_CFR_Part_11

    The manufacturer must use the hard copy (rather than electronic versions stored in the system) of the records for regulated activities. The current technical architecture of computer systems increasingly makes the Part 11, Electronic Records; Electronic Signatures — Scope and Application for the complete and accurate copy requirement ...

  4. Validation (drug manufacture) - Wikipedia

    en.wikipedia.org/wiki/Validation_(drug_manufacture)

    As part of a risk management system, decisions on the extent of validation and data integrity controls should be based on a justified and documented risk assessment of the computerised system." The subsequent validation or verification of computer systems targets only the "GxP critical" requirements of computer systems. Evidence (e.g. screen ...

  5. Good automated manufacturing practice - Wikipedia

    en.wikipedia.org/wiki/Good_Automated...

    ISPE has published a series of good practice guides for the industry on several topics involved in drug manufacturing. The most well-known is The Good Automated Manufacturing Practice (GAMP) Guide for Validation of Automated Systems in Pharmaceutical Manufacture. The second edition (GAMP5) was released in July 2022. [2]

  6. Design controls - Wikipedia

    en.wikipedia.org/wiki/Design_controls

    ISO 13485 is a voluntary standard that contains section 7.3 Design and Development recommending which procedures should be put in place by manufacturers in order to have a quality system that will comply with MDD 93/42/EEC and the MDR.

  7. Verification and validation - Wikipedia

    en.wikipedia.org/wiki/Verification_and_validation

    Verification and validation (also abbreviated as V&V) are independent procedures that are used together for checking that a product, service, or system meets requirements and specifications and that it fulfills its intended purpose. [1] These are critical components of a quality management system such as ISO 9000. The words "verification" and ...

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  9. FIPS 140 - Wikipedia

    en.wikipedia.org/wiki/FIPS_140

    FIPS 140-1 and FIPS 140-2 validation certificates specify the exact module name, hardware, software, firmware, and/or applet version numbers. For Levels 2 and higher, the operating platform upon which the validation is applicable is also listed. Vendors do not always maintain their baseline validations.

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