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  2. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Tranquillizers, sleeping pills, opiates and alcohol. Opioid-related deaths often involve alcohol. Concerns exist about a number of pharmacological pairings, especially: Antidepressants MAOIs combined with most drug classes, especially stimulants. SSRIs combined with MAOIs, or opioids. Depressants combined with depressant. For example:

  3. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. [ 9 ] [ 10 ] A 2005 medical review advised patients to avoid all citrus juices until further research clarifies the risks. [ 11 ]

  4. Disulfiram-alcohol reaction - Wikipedia

    en.wikipedia.org/wiki/Disulfiram-alcohol_reaction

    Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [1] [2] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [3] [4] use).

  5. Weight-Loss Drugs May Help Alcohol and Opioid Addiction

    www.aol.com/weight-loss-drugs-may-help-142951096...

    Research hints that medications like Zepbound and Wegovy could provide new ways to treat opioid and alcohol abuse.

  6. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    This combination's goal is to prolong the empathogenic effects of MDMA and the psychedelic effects of LSD. The idea is to have be able to experience an enhanced "Candyflipping" with a smoother comedown. The whole experience is long-lasting and can be too intense as all of these molecules synergize and potentiate each other. 2C-B: MDMA: Nexus ...

  7. Alcohol (drug) - Wikipedia

    en.wikipedia.org/wiki/Alcohol_(drug)

    Tranquillizers, sleeping pills, opiates and alcohol. Opioid-related deaths often involve alcohol. Alcohol can intensify the sedation caused by hypnotics/sedatives such as barbiturates, benzodiazepines, sedative antihistamines, opioids, nonbenzodiazepines/Z-drugs (such as zolpidem and zopiclone). [233]

  8. He kicked alcohol, became addicted to wellness drink that ...

    www.aol.com/news/kicked-alcohol-became-addicted...

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  9. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    In the United States five medications are approved to treat alcohol and opioid use disorders. [53] There are no approved medications for cocaine, methamphetamine. [53] [54] Medications, such as methadone and disulfiram, can be used as part of broader treatment plans to help a patient function comfortably without illicit opioids or alcohol. [55]