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The concerns began with the hypothesis that BPA is an endocrine disruptor, i.e. it mimics endocrine hormones and thus has the unintended and possibly far-reaching effects on people in physical contact with the chemical. Since 2008, several governments have investigated its safety, which prompted some retailers to withdraw polycarbonate products.
Health impacts of endocrine disruptors The growing scientific literature suggests that endocrine disruptors could play a part in conditions including attention deficit disorder and impulse control ...
Endocrine-disrupting chemicals like BPA, phthalates, and PFAS are widespread in consumer products ... Since endocrine disruptors interfere with sex steroid hormones, sex differences can be ...
Furthermore, BPA is just one of many endocrine disruptors people encounter daily. The cumulative impact of exposure to multiple chemicals, known as the “chemical cocktail effect,” could ...
In this way, xenohormones act as endocrine disruptors by increasing or decreasing the activation of hormone receptors in the body. Xenohormones can often act on multiple hormone receptor types and enact multiple different effects. For example, BPA acts as an agonist of estrogen receptors and as an antagonist of androgen receptors. [15]
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is soluble in most common organic solvents, but has very poor solubility in water. [2] [7] BPA is produced on an industrial scale by the condensation reaction of phenol and acetone. Global production in 2022 was ...
What are endocrine disruptors? Endocrine disruptors are chemicals that interfere with our endocrine systems, which control the body’s hormones—such as insulin, testosterone, and estrogen—and ...