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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as laxatives and as stool softeners, by mouth or rectally. [1]
Stool softener laxatives: Colace (docusate sodium) ... However, there may be some short-term side effects, such as diarrhea, nausea, bloating, vomiting, or stomach pain. Normally, these are ...
Emollient laxatives, also known as stool softeners, are anionic surfactants that enable additional water and fats to be incorporated in the stool, making movement through the bowels easier. Properties. Site of action: small and large intestines; Onset of action: 12–72 hours; Examples: Docusate (Colace, Diocto), Gibs-Eze [3]
Side effects may include increased bowel gas, abdominal pain, and nausea. [1] Rare but serious side effects may include an abnormal heartbeat, seizures, and kidney problems. [6] Use appears to be safe during pregnancy. [7] [1] It is classified as an osmotic laxative: [2] It works by increasing the amount of water in the stool. [3]
Docusate sodium (Colace) is a helpful stool softener if constipation is provoking your hemorrhoids, ... When in doubt, err on the side of caution and book that appointment. “It is important for ...
Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM, BHPM).
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