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A fibroepithelial neoplasm (or tumor) is a biphasic tumor. They consist of epithelial tissue, and stromal or mesenchymal tissue. They may be benign or malignant. [1] Examples include: Brenner tumor of the ovary; Fibroadenoma of the breast; Phyllodes tumor of the breast; Sometimes fibroepithelial polyps (FEPs) of the vulva may be misdiagnosed as ...
Phyllodes tumors are part of a group of breast diseases called cellular fibroepithelial lesions. [8] This term incorporates a spectrum of diseases ranging from a benign fibroadenoma to a malignant phyllodes tumor, with numerous variants in between. [14] They are classified by ICD-O, not by MeSH. [14]
Either case commonly presents as a breast lump. Approximately 7% of breast lumps are fibroadenomas and 10% are breast cancer, the rest being other benign conditions or no disease. [4] Phyllodes tumor is a fibroepithelial tumor which can be benign, borderline or malignant.
Fibroadenoma of the breast is a benign tumor composed of a biplastic proliferation of both stromal and epithelial components. [ 12 ] [ 13 ] This biplasia can be arranged in two growth patterns: pericanalicular (stromal proliferation around epithelial structures) and intracanalicular (stromal proliferation compressing the epithelial structures ...
A breast mass, also known as a breast lump, is a localized swelling that feels different from the surrounding tissue. [1] Breast pain, nipple discharge, or skin changes may be present. [1] Concerning findings include masses that are hard, do not move easily, are of an irregular shape, or are firmly attached to surrounding tissue. [2]
Pseudoangiomatous stromal hyperplasia (PASH) is an overgrowth of myofibroblastic cells in the breast. It has an appearance similar to fibroadenomatoid changes. [1] The diagnostic significance is currently uncertain, but it appears to be benign. There have been cases of PASH diagnosed where the tumors co-exist with breast cancer.
Fibrocystic breast changes is a condition of the breasts where there may be pain, breast cysts, and breast masses. [1] The breasts may be described as "lumpy" or "doughy". [3] Symptoms may worsen during certain parts of the menstrual cycle due to hormonal stimulation. [1] These are normal breast changes, not associated with cancer. [2]
For example, a lipoma is a common benign tumor of fat cells , and a chondroma is a benign tumor of cartilage-forming cells (chondrocytes). Adenomas are benign tumors of gland-forming cells, and are usually specified further by their cell or organ of origin, as in hepatic adenoma (a benign tumor of hepatocytes, or liver cells).
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