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Solifenacin, sold as the brand name Vesicare [a] among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). [1] [2] It may help with incontinence, urinary frequency, and urinary urgency.
Propiverine is an anticholinergic drug used for the treatment of urinary urgency, frequency and urge incontinence, all symptoms of overactive bladder syndrome. [2] [3] It is a muscarinic antagonist. [4]
Trospium chloride is used for the treatment of overactive bladder with symptoms of urge incontinence and frequent urination. [3] [4] [2]It should not be used with people who retain urine, who have severe digestive conditions, myasthenia gravis, narrow-angle glaucoma, or tachyarrhythmia.
In late or severe stage of overdose, it could lead to coma, medullary paralysis, death. Physostigmine structure. Supportive care is usually performed in anticholinergic toxicated patients. Intravenous benzodiazepine is used as a first-line treatment for agitation. Cooling measures are employed if there is any significant hyperthermia.
Darifenacin is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency in adults. It may also be recommended with an alpha blocker to help provide symptomatic benefit for overactive bladder and obstructive symptoms such as those likely associated with benign prostatic hyperplasia .
Medications are not recommended for those with stress incontinence and are only recommended in those with urge incontinence who do not improve with bladder training. [44] While medications have been shown to be helpful with treating urinary incontinence, studies have shown that the first line treatment that's most effective against urinary ...
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