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  2. Endochondral ossification - Wikipedia

    en.wikipedia.org/wiki/Endochondral_ossification

    A schematic for long bone endochondral ossification. In developing bones, ossification commences within the primary ossification center located in the center of the diaphysis (bone shaft), [5] where the following changes occur: The perichondrium surrounding the cartilage model transforms into the periosteum. During this transformation, special ...

  3. Newton's laws of motion - Wikipedia

    en.wikipedia.org/wiki/Newton's_laws_of_motion

    In a later manuscript, Newton added a law of action and reaction, while saying that this law and the law regarding the center of mass implied one another. Newton probably settled on the presentation in the Principia, with three primary laws and then other statements reduced to corollaries, during 1685. [125]

  4. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).

  5. Development of joints - Wikipedia

    en.wikipedia.org/wiki/Development_of_joints

    The bones that form the base and facial regions of the skull develop through the process of endochondral ossification. In this process, mesenchyme accumulates and differentiates into hyaline cartilage, which forms a model of the future bone. The hyaline cartilage model is then gradually, over a period of many years, displaced by bone.

  6. Bone remodeling - Wikipedia

    en.wikipedia.org/wiki/Bone_remodeling

    Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).

  7. De motu corporum in gyrum - Wikipedia

    en.wikipedia.org/wiki/De_motu_corporum_in_gyrum

    Later, in 1686, when Newton's Principia had been presented to the Royal Society, Hooke claimed from this correspondence the credit for some of Newton's content in the Principia, and said Newton owed the idea of an inverse-square law of attraction to him – although at the same time, Hooke disclaimed any credit for the curves and trajectories ...

  8. Osteoblast - Wikipedia

    en.wikipedia.org/wiki/Osteoblast

    Endochondral ossification is the process of forming bone from cartilage and this is the usual method. This form of bone development is the more complex form: it follows the formation of a first skeleton of cartilage made by chondrocytes, which is then removed and replaced by bone, made by osteoblasts. Intramembranous ossification is the direct ...

  9. Bone healing - Wikipedia

    en.wikipedia.org/wiki/Bone_healing

    It usually consists of only endochondral ossification. Sometimes, intramembranous ossification occurs together with endochondral ossification. Intramembranous ossification, mediated by the periosteal layer of bone, occurs with the formation of callus. For endochondral ossification, deposition of bone only occurs after the mineralised cartilage.