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Pattern hair loss (also known as androgenetic alopecia (AGA) [1]) is a hair loss condition that primarily affects the top and front of the scalp. [2] [3] In male-pattern hair loss (MPHL), the hair loss typically presents itself as either a receding front hairline, loss of hair on the crown and vertex of the scalp, or a combination of both.
It’s also called male pattern hair loss or male pattern baldness. But DHT — and androgenetic alopecia, for that matter — aren't exclusive to men. Women also make some testosterone.
Male pattern baldness (androgenetic alopecia) is a common issue that can happen to men of all ages. It can cause diffuse hair loss across the entire scalp, a receding hairline, a bald patch, or a ...
5α-Reductase type 2 (5αR2) is an enzyme, encoded by the SRD5A2 gene, that is expressed in specific tissues in the male body from fetal development to adulthood. [4] [10] [11] The enzyme catalyzes the transformation of testosterone (T) to 5α-dihydrotestosterone (DHT) intracellularly.
Testosterone is the primary androgen — or male hormone — in your body. Low testosterone affects up to 39 percent of adult men in the US over the age of 45, and becomes increasingly prevalent ...
Male pattern hair loss is treated with oral finasteride which is a 5-alpha reductase inhibitor that blocks the formation of DHT from testosterone. Finasteride may cause sexual dysfunction, but it is typically reversed upon discontinuation of the treatment. [ 13 ]
Losing facial and body hair can also be a symptom of low testosterone in men. However, hair loss on the head is typically not a sign of low testosterone. Male pattern baldness is predominantly ...
In male-pattern hair loss, loss and thinning begin at the temples and the crown and hair either thins out or falls out. Female-pattern hair loss occurs at the frontal and parietal. People have between 100,000 and 150,000 hairs on their head. The number of strands normally lost in a day varies but on average is 100. [9]