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The glycocalyx is located on the apical surface of vascular endothelial cells which line the lumen.When vessels are stained with cationic dyes such as Alcian blue stain, transmission electron microscopy shows a small, irregularly shaped layer extending approximately 50–100 nm into the lumen of a blood vessel.
A glycocalyx surface coat contains digestive enzymes. Microvilli on the apical surface increase its surface area. This facilitates transport of numerous small molecules into the enterocyte from the intestinal lumen. These include broken down proteins, fats, and sugars, as well as water, electrolytes, vitamins, and bile salts.
The glycocalyx is an important feature in all cells, especially epithelia with microvilli. Recent data suggest the glycocalyx participates in cell adhesion, lymphocyte homing, [26] and many others. The penultimate sugar is galactose and the terminal sugar is sialic acid, as the sugar backbone is modified in the Golgi apparatus. Sialic acid ...
The brush border on the apical surface of the epithelial cells is covered with glycocalyx, which is composed of oligosaccharides attached to membrane glycoproteins and glycolipids. [7] TEM image of a thin section cut through an epithelial cell showing the luminal surface (apical end) of the cell packed with microvilli that make up the absorbing ...
Capsule and slime layer are sometimes summarized under the term glycocalyx. A bacterial capsule has a semi-rigid border that follows the contour of the cell. The capsule excludes India Ink when dyed. A slime layer is a non-rigid matrix that is easily deformed and is not able to exclude India Ink.
The plus ends of the actin filaments are located at the tip of the microvillus and are capped, possibly by capZ proteins, [2] while the minus ends are anchored in the terminal web composed of a complicated set of proteins including spectrin and myosin II. The space between microvilli at a cell's surface is called the intermicrovillous space.
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The red blood cell membrane is composed of 3 layers: the glycocalyx on the exterior, which is rich in carbohydrates; the lipid bilayer which contains many transmembrane proteins, besides its lipidic main constituents; and the membrane skeleton, a structural network of proteins located on the inner surface of the lipid bilayer. Half of the ...