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Grb2 is best known for its ability to link the epidermal growth factor receptor tyrosine kinase to the activation of Ras and its downstream kinases, ERK1,2. Grb2 is composed of an SH2 domain flanked on each side by an SH3 domain. Grb2 has two closely related proteins with similar domain organizations, Gads and Grap.
Cell division, growth, and proliferation. Cell proliferation is the process by which a cell grows and divides to produce two daughter cells. [1] [2] [3] [4] Cell ...
The first atomic structures of the ribosome complexed with tRNA and mRNA molecules were solved by using X-ray crystallography by two groups independently, at 2.8 Å [44] and at 3.7 Å. [45] These structures allow one to see the details of interactions of the Thermus thermophilus ribosome with mRNA and with tRNAs bound at classical ribosomal sites.
Mn 2+ is very similar to Mg 2+ in terms of its chemical properties, including inner and outer shell complexation. Mn 2+ effectively binds ATP and allows hydrolysis of the energy molecule by most ATPases. Mn 2+ can also replace Mg 2+ as the activating ion for a number of Mg 2+-dependent enzymes, although some enzyme activity is usually lost. [56]
Clonality implies the state of a cell or a substance being derived from one source or the other. Thus there are terms like polyclonal—derived from many clones; oligoclonal [2] —derived from a few clones; and monoclonal—derived from one clone. These terms are most commonly used in context of antibodies or immunocytes.
Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. [2] Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system.
Get ready for all of today's NYT 'Connections’ hints and answers for #552 on Saturday, December 14, 2024. Today's NYT Connections puzzle for Saturday, December 14, 2024 The New York Times
Illustration of the malate–aspartate shuttle pathway. The malate–aspartate shuttle (sometimes simply the malate shuttle) is a biochemical system for translocating electrons produced during glycolysis across the semipermeable inner membrane of the mitochondrion for oxidative phosphorylation in eukaryotes.