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  2. Things You Probably Don't Know About Viagra (Like What ... - AOL

    www.aol.com/things-probably-dont-know-viagra...

    Likewise, Viagra shouldn’t be combined with antiretroviral drugs used to treat HIV/AIDS, as it can cause an increased concentration of sildenafil in the body. Breastfeeding women shouldn’t ...

  3. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    In 1833 French chemist Anselme Payen was the first to discover an enzyme, diastase. In 1834, François Mothes and Joseph Dublanc created a method to produce a single-piece gelatin capsule that was sealed with a drop of gelatin solution. In 1853 Alexander Wood was the first physician that used hypodermic needle to dispense drugs via Injections.

  4. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    Research involving more than 1,900 college-age men found that four percent of otherwise healthy undergraduates reported recreationally using ED drugs like Viagra.

  5. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  6. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Pfizer originally discovered the medication in 1989 while looking for a treatment for angina. [11] It was approved for medical use in the United States and in the European Union in 1998. [ 5 ] [ 8 ] [ 11 ] [ 12 ] In 2022, it was the 157th most commonly prescribed medication in the United States, with more than 3 million prescriptions.

  7. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

    www.aol.com/does-viagra-actually-intimate...

    Viagra’s main ingredient sildenafil is part of a class of drugs referred to as PDE5 inhibitors, which (unlike non-prescription supplements) are approved by the FDA for the treatment of ED.

  8. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Though ED pills work at different speeds based on their ingredients, most sexual dysfunction drugs take 30 to 60 minutes to start working with stimulation. ... natural chemical compounds that have ...

  9. Lydia Pinkham - Wikipedia

    en.wikipedia.org/wiki/Lydia_Pinkham

    Lydia Estes Pinkham (born Estes; February 9, 1819 – May 17, 1883) was an American inventor and marketer of a herbal-alcoholic "women's tonic" for menstrual and menopausal problems, which medical experts dismissed as a quack remedy, but which is still on sale today in a modified form.