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  2. Venlafaxine - Wikipedia

    en.wikipedia.org/wiki/Venlafaxine

    Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [6] [9] It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. [9]

  3. Serotonin–norepinephrine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    The half-life of desvenlafaxine is about 11 hours, and steady-state concentrations are achieved after 4 to 5 days. [58] The half-life of duloxetine is about 12 hours (range: 8–17 hours), and steady-state is achieved after about 3 days. [11] Milnacipran has a half-life of about 6 to 8 hours, and steady-state levels are reached within 36 to 48 ...

  4. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Fluoxetine also has a long half-life which can reduce withdrawal symptoms which are characteristic for some SSRIs after abrupt discontinuation, but it also means that it takes a long time to clear the drug and its active metabolite after discontinuing fluoxetine treatment. [18] Figure 5 Chemical structure of (–)-(3S,4R)-paroxetine

  5. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t ⁠ 1 / 2 ⁠ ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...

  6. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    Venlafaxine has also been implicated to create withdrawal symptoms regardless of dosage. [15] Venlafaxine has been implicated in causing the most severe withdrawal symptoms after cessation of use, possibly due to its short half-life. [16] To simplify identifying the principal signs and symptoms, the mnemonic FINISH may be used: Flu-like ...

  7. List of antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_antidepressants

    12 Atypical antipsychotics. 13 Others. Toggle Others subsection. 13.1 Marketed. ... Venlafaxine (Effexor, Trevilor) Serotonin–dopamine reuptake inhibitor (SDRIs)

  8. Things You Probably Don't Know About Viagra (Like What It Was ...

    www.aol.com/things-probably-dont-know-viagra...

    Whether you’re a senior in high school or a senior-living resident, you’ve likely heard of Viagra (sildenafil) — the original medication for ED. Most men and women know at least vaguely what ...

  9. Half-life - Wikipedia

    en.wikipedia.org/wiki/Half-life

    In this situation it is generally uncommon to talk about half-life in the first place, but sometimes people will describe the decay in terms of its "first half-life", "second half-life", etc., where the first half-life is defined as the time required for decay from the initial value to 50%, the second half-life is from 50% to 25%, and so on. [7]

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