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[19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...
That's why it's important to find out from your health care provider or a pharmacist if any of your medications interact with grapefruit. In addition, grapefruit can have the opposite effect on ...
For other drugs, grapefruit may conversely interfere with a protein needed to transport certain medications into your body’s cells. This has the opposite effect, decreasing the drug’s ...
Important: If you're taking statins or medications for conditions like high blood pressure, cholesterol, heart arrhythmia, organ transplants, or allergies, it can be dangerous to eat grapefruit ...
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs .
Grapefruit decreased drug metabolism in humans, which likely represented the first clinical example of a food producing such an effect. Clinically, the concern is that a single judicious amount of grapefruit ingested even many hours beforehand would noticeably boost oral drug bioavailability and cause overdose toxicity.
A single glass of grapefruit juice can interfere with your body's ability to break down a medication. Here's how to protect your health.