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Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system. Classification [ edit ]
Immunosuppression is a reduction of the activation or efficacy of the immune system.Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.
Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants [10] and as a targeted therapy in the treatment of renal cell cancer and other tumours. [11] This compound also has a use in cardiovascular drug-eluting stent technologies to inhibit restenosis.
Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, eczema, and in organ transplants to prevent rejection.
Mycophenolic acid is an immunosuppressant medication used to prevent rejection following organ transplantation and to treat autoimmune conditions such as Crohn's disease and lupus. [13] [14] Specifically it is used following kidney, heart, and liver transplantation. [14] It can be given by mouth or by injection into a vein. [14]
The American Heritage Dictionary of the English Language (abbreviated AHD) uses a phonetic notation based on the Latin alphabet to transcribe the pronunciation of spoken English. It and similar respelling systems, such as those used by the Merriam-Webster and Random House dictionaries, are familiar to US schoolchildren.
If you feel it is necessary to add a pronunciation respelling using another convention, then please use the conventions of Wikipedia's pronunciation respelling key. To compare the following IPA symbols with non-IPA American dictionary conventions that may be more familiar, see Pronunciation respelling for English , which lists the pronunciation ...
Azathioprine, sold under the brand name Imuran, among others, is an immunosuppressive medication. [5] It is used for the treatment of rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus, and in kidney transplants to prevent rejection.