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Leptospirosis is a blood infection caused by the bacterium Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild ( headaches , muscle pains , and fevers ) to severe ( bleeding in the lungs or meningitis ). [ 5 ]
Leptospirosis is treated in humans by the antibiotics penicillin and doxycycline. [7] [8] L. interrogans has many properties that ensure its optimal survival in specific conditions, including two periplasmic flagella for movement and mobility. These flagella enable L. interrogans to more easily access and infect both human and mammalian tissues ...
Although over 200 serotypes of Leptospira have been described, all members of the genus have similar morphology. Leptospira are spiral-shaped bacteria that are 6-20 μm long and 0.1 μm in diameter with a wavelength of about 0.5 μm. [18] One or both ends of the spirochete are usually hooked.
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Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7] The disease is normally absorbed through the mucous membranes of another animal or human and is excreted from the body in the urine. [ 7 ]
OTC (over the counter) products containing cetylpyridinium chloride include oral wash, oral rinse, and ingestable products, such as lozenges [8] and over-the-counter cough syrup. [9] The United States' federal Food and Drug Administration's monograph on oral antiseptic drug products reviewed the data regarding CPC and made this conclusion:
The cream contains 4% lidocaine, the FDA-approved maximum strength for over-the-counter use. This makes it excellent for those with moderate to severe arthritis pain. The cream numbs the pain ...
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