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Results released in February 2009 from a clinical trial of PRO 2000 (Indevus Pharmaceuticals), a vaginal-microbicide gel (0.5%), sparked hope that it might provide modest protection against HIV. [22] The results of a larger trial released in December 2009 showed that PRO 2000 was safe as administered, but was ineffective in reducing the risk of ...
The ideal vaginal microbicide would have the following characteristics: provide protection against infection not require application at the time of intercourse not harm the natural tissue [3] As of 2009, not harming natural tissue was the most troublesome aspect of development.
As we go through the changes of perimenopause and menopause, vaginal dryness can cause discomfort and itching. Applying an over-the-counter vaginal moisturizer, such as Replens, can help. These ...
To combat dryness in general, you can also try vaginal moisturizers (like Replens), which are “used more on a chronic basis, like every day or every other day, to help prevent dryness,” Dr ...
“The most common cause of vaginal odor is an imbalance in the normal flora in the vagina,” which causes a fishy odor, irritation, and thin to no vaginal discharge, says Dr. Streicher.
Formulation methods include vaginal tablets, vaginal cream, vaginal gel, [4] vaginal suppository and vaginal ring. Medicines primarily delivered by intravaginal administration include vaginally administered estrogens and progestogens (a group of hormones including progesterone ), and antibacterials and antifungals to treat bacterial vaginosis ...
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