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Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
This is an accepted version of this page This is the latest accepted revision, reviewed on 15 November 2024. British X-ray crystallographer (1920–1958) This article is about the chemist. For the Mars rover named after her, see Rosalind Franklin (rover). Rosalind Franklin Franklin with a microscope in 1955 Born Rosalind Elsie Franklin (1920-07-25) 25 July 1920 Notting Hill, London, England ...
Other forms of elastic X-ray scattering besides single-crystal diffraction include powder diffraction, small-angle X-ray scattering and several types of X-ray fiber diffraction, which was used by Rosalind Franklin in determining the double-helix structure of DNA. In general, single-crystal X-ray diffraction offers more structural information ...
Rosalind Franklin joined King's College London in January 1951 to work on the crystallography of DNA. By the end of that year, she established two important facts: one is that phosphate groups, which are the molecular backbone for the nucleotide chains, lie on the outside (it was a general consensus at the time that they were at the inside); and the other is that DNA exists in two forms, a ...
The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...
A powder X-ray diffractometer in motion. X-ray crystallography is the experimental science of determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract in specific directions.
After the initial work producing the first x-ray diffraction of DNA, Randall reassigned Gosling to work with Rosalind Franklin, who had been just hired to join King's College in 1951. He did this without consulting with Wilkins, a factor which may have contributed to the animosity between the two.
The first high quality X-ray diffraction patterns of A-DNA were reported by Rosalind Franklin and Raymond Gosling in 1953. [1] Rosalind Franklin made the critical observation that DNA exists in two distinct forms, A and B, and produced the sharpest pictures of both through X-ray diffraction technique. [2]
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