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HLA matching improves kidney, heart, and lung graft survival, but an HLA-based (ABO, HLA, lymphocytotoxicity cross-match) donor organ allocation has been implemented only for kidney transplantation.
Drs Kathy Miller and Nancy U. Lin discuss central nervous system involvement in HER2 positive breast cancer, including the biology and management of patients.
Since ivermectin can't cross the blood-brain barrier, we are spared from its effects. ... In fact, standard ivermectin dosing achieves blood concentrations of about 25 nanomolar, 100-fold less ...
The researchers found that fibrin, a major component involved in blood clotting, can extravasate into the brain. "The blood–brain barrier can break down in Alzheimer's, so things from the blood ...
Free thiamine is not lipophilic and cannot cross the blood-brain barrier by simple diffusion. Transport of blood thiamine to the brain parenchyma is carrier-mediated and it is a slow process. [ 37 ]
The blood–brain barrier (BBB) is a significant obstacle to therapeutic delivery for CNS disorders. Among various strategies, nanobiotechnology plays an important role in facilitating drug ...
The arterioles in the retina narrowed by 0.13 pixels for every 10 mm Hg increase in systolic blood pressure (P < .001) and by 0.02 pixels for each mm Hg increase in eye pressure (P < .05).
Forms of passage of substances across the blood–brain barrier. (A) Passive diffusion: fat-soluble substances dissolve in the cell membrane and cross the barrier (e.g., alcohol, nicotine and ...
Additional criteria include blood pressure ≥ 130/85 mmHg and fasting blood glucose > 110 mg/dL. ... The prevalence of the metabolic syndrome was 21.8% in this cross-sectional population aged 20 ...
Acknowledgments. We thank Professor Julian Paton and Dr Oleg Osadchii for helpful discussions. Reprint Address. Alexander V Gourine, Department of Physiology, University College London, Gower ...