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  2. Tripartite Model of Anxiety and Depression - Wikipedia

    en.wikipedia.org/wiki/Tripartite_Model_of...

    The results of this study were congruent with low Positive Affect predicting depression. [20] A longitudinal study was completed with a sample of students in grade 6 and later grade 9. The students completed the Baltimore How I Feel (BHIF), a measure of anxious and depressive symptoms. This study confirmed the PA aspect of the tripartite model ...

  3. Neurogenesis hypothesis of depression - Wikipedia

    en.wikipedia.org/wiki/Neurogenesis_hypothesis_of...

    Neurogenesis hypothesis of depression. In humans, adult neurogenesis occurs in the subgranular zone of the dentate gyrus in the hippocampus (marked by 'DG' in the image) Adult neurogenesis is the process by which functional, mature neurons are produced from neural stem cells (NSCs) in the adult brain. In most mammals, including humans, it only ...

  4. Pit of despair - Wikipedia

    en.wikipedia.org/wiki/Pit_of_despair

    t. e. The pit of despair was a name used by American comparative psychologist Harry Harlow for a device he designed, technically called a vertical chamber apparatus, that he used in experiments on rhesus macaque monkeys at the University of Wisconsin–Madison in the 1970s. [2] The aim of the research was to produce an animal model of depression.

  5. A pacemaker for the brain helped a woman with crippling ... - AOL

    www.aol.com/news/pacemaker-brain-helped-woman...

    Emily Hollenbeck lived with a recurring depression she likened to a black hole, where gravity felt so strong and her limbs so heavy she could barely move. Researchers say the treatment — deep ...

  6. Animal models of depression - Wikipedia

    en.wikipedia.org/wiki/Animal_models_of_depression

    v. t. e. Animal models of depression are research tools used to investigate depression and action of antidepressants. They are used as a simulation to investigate the symptomatology and pathophysiology of depressive illness and to screen novel antidepressants. These models provide insights into molecular, genetic, and epigenetic factors ...

  7. Between-group design experiment - Wikipedia

    en.wikipedia.org/wiki/Between-group_design...

    Between-group design experiment. In the design of experiments, a between-group design is an experiment that has two or more groups of subjects each being tested by a different testing factor simultaneously. This design is usually used in place of, or in some cases in conjunction with, the within-subject design, which applies the same variations ...

  8. Depressive realism - Wikipedia

    en.wikipedia.org/wiki/Depressive_realism

    Depressive realism. Depressive realism is the hypothesis developed by Lauren Alloy and Lyn Yvonne Abramson [1] that depressed individuals make more realistic inferences than non-depressed individuals. Although depressed individuals are thought to have a negative cognitive bias that results in recurrent, negative automatic thoughts, maladaptive ...

  9. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [10] the term was adopted by the American Psychiatric ...