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2-Aminothiophenol is an organosulfur compound with the formula C 6 H 4 (SH)(NH 2). It is a colorless oily solid, although impure samples can be deeply colored. It is soluble in organic solvents and in basic water. 2-Aminothiophenol is a precursor to benzothiazoles, some of which are bioactive or are commercial dyes.
2-Aminophenol has a variety of uses. As a reducing agent, it is marketed under the names of Atomal and Ortol to develop black-and-white photographs. [3] 2-Aminophenol is an intermediate in the synthesis of dyes. It is particularly useful in yielding metal-complex dyes when diazotized and coupled to a phenol, naphthol, or other aromatic or ...
Benzimidazole is a base: C 6 H 4 N(NH)CH + H + → [C 6 H 4 (NH) 2 CH] + It can also be deprotonated with stronger bases: C 6 H 4 N(NH)CH + LiH → Li [C 6 H 4 N 2 CH] + H 2. The imine can be alkylated and also serves as a ligand in coordination chemistry. The most prominent benzimidazole complex features N-ribosyl-dimethylbenzimidazole, as ...
The structure-activity relationship of the drug class has been explored to a reasonable extent. The optimal substitution pattern is fairly tightly defined (i.e. N,N-diethyl on the amine nitrogen, 4-ethoxy on the benzyl ring and 5-nitro on the benzimidazole ring), but even derivatives incorporating only some of these features are still potent opioids.
The solubility of benzimidazole fungicides is low at physiological pH and becomes high at low pH. In plants, carbendazim, thiabendazole and fuberidazole are mobile, i.e. systemic, and benomyl and thiophanate-methyl are converted to carbendazim. [2] This conversion also occurs in soils and animals. [1]
The use of larger tube-based "macrodilution" testing has been superseded by smaller "microdilution" kits. [ 5 ] In 1966, the World Health Organisation confirmed the Kirby–Bauer method as the standard method for susceptibility testing; it is simple, cost-effective and can test multiple antibiotics.
2-Aminobiphenyl (2-ABP) is an organic compound with the formula C 6 H 5 C 6 H 4 NH 2. It is an amine derivative of biphenyl. It is a colorless solid, although aged samples can appear colored even black. [1] Palladacycles obtained from 2-aminobiphenyl are popular catalysts for cross-coupling. [2] It is prepared by hydrogenation of 2 ...
Protonitazene is a benzimidazole derivative with potent opioid effects which has been sold over the internet as a designer drug since 2019, and has been identified in various European countries, as well as Canada, the US and Australia. [1]