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The epidemiology of hepatitis D occurs worldwide. [1] Although the figures are disputed, a recent systematic review suggests that up to 60 million individuals could be infected. [ 2 ] The major victims are the carriers of the hepatitis B surface antigen ( HBsAg ), who become superinfected by the HDV, and intravenous drug users who are the group ...
There are many extensions to the STROBE Statement which cover a variety of different topic domains such as nutritional epidemiology, [5] [6] [7] genetic association studies, [8] rheumatology, [9] [10] molecular epidemiology, [11] infectious disease molecular epidemiology, [12] respondent-driven sampling, [13] routinely collected health data [14] [15] (e.g., health administrative data ...
Bradford Hill's criteria had been widely accepted as useful guidelines for investigating causality in epidemiological studies but their value has been questioned because they have become somewhat outdated. [5] In addition, their method of application is debated. [citation needed] Some proposed options how to apply them include:
The prenylation inhibitor lonafarnib prevents hepatitis D viral particle assembly by inhibiting the farnesylation of the L-HDAg. [53] REP2139-Ca is a nucleic acid polymer that prevents the release of hepatitis B surface antigen (which is required for assembly of hepatitis D viral particles). [54]
A lot of studies have well characterized the horizontal transmission of HBV through parenteral routes and co-infections with different genotypes of HBV have also been reported, including genotypes A and D, genotypes A and G, and genotypes B and C. In Asia, genotypes B and C account for almost all HBV infections.
The aim of the PRISMA statement is to help authors improve the reporting of systematic reviews and meta-analyses. [3] PRISMA has mainly focused on systematic reviews and meta-analysis of randomized trials, but it can also be used as a basis for reporting reviews of other types of research (e.g., diagnostic studies, observational studies).
Australia [1] Hong Kong [2] India [3] Malaysia [4] United Kingdom [5] United States [6]; Acquired Immunodeficiency Syndrome (AIDS) : Acquired immunodeficiency syndrome: Regional arbovirus infections: Barmah Forest, Murray Valley encephalitis virus infection, Ross River virus infection
Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [ 30 ]