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Melzack's description has been adapted by the International Association for the Study of Pain in a contemporary definition of pain. [1] Despite flaws in its presentation of neural architecture, the theory of gate control is currently the only theory that most accurately accounts for the physical and psychological aspects of pain. [2]
Wall & Melzack's Textbook of Pain is a medical textbook published by Elsevier. It is named after Patrick David Wall and Ronald Melzack, who introduced the gate control theory into pain research in the 1960s. First released in 1984, the book has been described as "the most comprehensive scientific reference text in the field of pain medicine".
Ronald Melzack OC OQ FRSC (July 19, 1929 – December 22, 2019) was a Canadian psychologist and professor of psychology at McGill University. [1] [2] In 1965, he and Patrick David Wall re-charged pain research by introducing the gate control theory of pain.
He was the principal advocate of the cardio-centric theory of the soul, and differed in this from the encephalo-centric proposals of, among others, Hippocrate, who explicitly considered that the brain was the source of "our pains, grief, anxieties and tears" (Hippocrates, in: W.H.S. Jones (Ed.), The Sacred Disease, vol. 2, The Loeb Classical ...
At Melzack's urging they wrote a paper on the Gate control theory of pain and published it in Brain in 1962; according to Wall it was read by around three people. After expanding and rewriting the article they republished it as Pain Mechanisms: a new theory in Science in 1965 where it drew wider attention, with mostly negative comments. [11]
Gate Control Theory Firing of the inhibitory interneuron (responding to the non-painful stimuli) decreases the probability that the projection neuron (responsible for pain responses) will fire an action potential. The wide dynamic range (WDR) neuron was first discovered by Mendell in 1966. [1]
Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage."
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