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Xanomeline/trospium chloride, sold under the brand name Cobenfy, is a fixed-dose combination medication used for the treatment of schizophrenia. [1] It contains xanomeline , a muscarinic agonist ; and trospium chloride , a muscarinic antagonist . [ 1 ]
Xanomeline/trospium, sold under the brand name Cobenfy, is an approved combination drug used in the treatment of schizophrenia. [ 6 ] [ 7 ] Trospium chloride is a peripherally selective non-selective muscarinic antagonist to quell peripheral muscarinic agonist-dependent side effects.
N o new treatments for schizophrenia have been approved in nearly three decades, but that changed on Sept. 26, when the U.S. Food and Drug Administration (FDA) approved Cobenfy for the psychiatric ...
On 26 September 2024, The Food and Drug Administration has given approval to one of Bristol Myers Squibb’s most anticipated schizophrenia drugs named Cobenfy which is the first novel type of treatment for the devitalizing, chronic mental disorder in the last 70 years. [90]
The labeling information of the treatment, Cobenfy, does not include a warning about the risk of increased mortality in some elderly patients, unlike other commonly used drugs for the disorder.
The U.S. Food and Drug Administration (FDA) on Thursday approved the first new drug to treat people with schizophrenia in more than 30 years. Cobenfy, manufactured by Bristol Myers Squibb ...
The fixed-dose combination medication xanomeline/trospium chloride (Cobenfy) was approved for medical use in the United States in September 2024. [ 201 ] [ 202 ] It is the first cholinergic agonist approved by the US Food and Drug Administration (FDA) to treat schizophrenia.
The company has executed several strategic acquisitions, including Karuna Therapeutics, which brought the recently approved schizophrenia treatment Cobenfy to its neuroscience portfolio. Wall ...
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