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Bronchiolitis obliterans when it occurs following a lung transplant is known as bronchiolitis obliterans syndrome (BOS). [11] [4] BOS is defined as a person who has had either a HSCT or lung transplant and develops symptoms or radiographic findings consistent with bronchiolitis obliterans, but has not been confirmed by biopsy. [22] [44]
Cryptogenic organizing pneumonia (COP), formerly known as bronchiolitis obliterans organizing pneumonia (BOOP), is an inflammation of the bronchioles (bronchiolitis) and surrounding tissue in the lungs. [2] [3] It is a form of idiopathic interstitial pneumonia. [4]
Bronchiolitis typically affects infants and children younger than two years, principally during the autumn and winter. [15] It is the leading cause of hospital admission for respiratory disease among infants in the United States and accounts for one out of every 13 primary care visits. [ 8 ]
Typical symptoms are of recurrent respiratory tract infections, but some have no symptoms. [2] As a result of childhood bronchiolitis obliterans, typically following adenovirus infection, there is a reduction in blood vessels and overextended alveoli, resulting in air trapping in one or part of one lung. [1]
A number of DPB symptoms resemble those found with other obstructive lung diseases such as asthma, chronic bronchitis, and emphysema. Wheezing, coughing with sputum production, and shortness of breath are common symptoms in such diseases, and obstructive respiratory functional impairment is found on pulmonary function testing. [6]
Respiratory bronchiolitis is a lung disease associated with tobacco smoking. [1] In pathology, it is defined by the presence of " smoker's macrophages ". [ 1 ] When manifesting significant clinical symptoms it is referred to as respiratory bronchiolitis interstitial lung disease (RB-ILD).
For children younger than 15 years old, nasopharyngel catheters or nasal prongs are recommended over a face mask or head box. [26] A Cochrane review in 2014 presented a summary to identify children complaining of severe LRTI, however; further research is required to determine the effectiveness of supplemental oxygen and the best delivery method ...
Up to one in five infants with bronchiolitis will have adenovirus infection, which can be severe. [2] Bronchiolitis obliterans is uncommon, but can occur if adenovirus causes pneumonia with prolonged fever, and can result in difficulty breathing. [2] It presents with a hyperinflated chest, expiratory wheeze and low oxygen. [2]