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The immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens , from viruses to bacteria , as well as cancer cells , parasitic worms , and also objects such as wood splinters , distinguishing them from the organism's own healthy tissue .
The history of immunology and the medical study of the immune system dates back to the 19th century. The first Nobel Prize in the field of immunogenetics was awarded to Baruj Benacerraf, Jean Dausset and George Davis Snell in 1980 for discovering genetically determined cellular surface structures, which control immunological reactions.
Immunology is a branch of biology and medicine [1] that covers the study of immune systems [2] in all organisms.. Immunology charts, measures, and contextualizes the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as autoimmune diseases, hypersensitivities, [3] immune deficiency, [4] and ...
This allows the innate immune system to recognize pathogens and thus, protect the host from infection. [ 3 ] : 494 Although the term "PAMP" is relatively new, the concept that molecules derived from microbes must be detected by receptors from multicellular organisms has been held for many decades, and references to an "endotoxin receptor" are ...
The following outline is provided as an overview of and topical guide to immunology: . Immunology – study of all aspects of the immune system in all organisms. [1] It deals with the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency ...
Tissue grafts are normally recognised as foreign antigens by the body and attacked by the immune system. However, in immune privileged sites, tissue grafts can survive for extended periods of time without rejection occurring. [1] Immunologically privileged sites include: the eyes; the placenta and fetus; the testicles; the central nervous system
The immune system refers to all of the cells, tissues, organs and processes that protect an organism from invasion by pathogens. Viruses , bacteria , parasites , and some toxins are some of pathogens that the immune system is involved in eliminating from the body.
In immunology, clonal selection theory explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body. The concept was introduced by Australian doctor Frank Macfarlane Burnet in 1957, in an attempt to explain the great diversity of antibodies formed during initiation of the immune response .