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  2. File:Signal Transduction Diagram- Insulin.svg - Wikipedia

    en.wikipedia.org/wiki/File:Signal_Transduction...

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  3. Insulin signal transduction pathway - Wikipedia

    en.wikipedia.org/wiki/Insulin_signal...

    The insulin transduction pathway is a biochemical pathway by which insulin increases the uptake of glucose into fat and muscle cells and reduces the synthesis of glucose in the liver and hence is involved in maintaining glucose homeostasis. This pathway is also influenced by fed versus fasting states, stress levels, and a variety of other ...

  4. File:Insulin glucose metabolism ZP.svg - Wikipedia

    en.wikipedia.org/wiki/File:Insulin_glucose...

    English: Effect of insulin on glucose uptake and metabolism. Insulin binds to its receptor (1), which in turn starts many protein activation cascades (2). These include: translocation of Glut-4 transporter to the plasma membrane and influx of glucose (3), glycogen synthesis (4), glycolysis (5) and fatty acid synthesis (6).

  5. File:Proinsuline schematic topological diagram.svg - Wikipedia

    en.wikipedia.org/wiki/File:Proinsuline_schematic...

    You are free: to share – to copy, distribute and transmit the work; to remix – to adapt the work; Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses ...

  6. File:Human Metabolism - Pathways.jpg - Wikipedia

    en.wikipedia.org/wiki/File:Human_Metabolism...

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  7. Beta cell - Wikipedia

    en.wikipedia.org/wiki/Beta_cell

    GLP-1 receptor agonists stimulate insulin secretion by simulating activation of the body's endogenous incretin system. [32] The incretin system acts as an insulin secretion amplifying pathway. [32] DPP-4 inhibitors block DPP-4 activity which increases postprandial incretin hormone concentration, therefore increasing insulin secretion. [32]

  8. Blood sugar regulation - Wikipedia

    en.wikipedia.org/wiki/Blood_sugar_regulation

    Diabetes mellitus type 1 is caused by insufficient or non-existent production of insulin, while type 2 is primarily due to a decreased response to insulin in the tissues of the body (insulin resistance). Both types of diabetes, if untreated, result in too much glucose remaining in the blood (hyperglycemia) and many of the same complications.

  9. GLUT4 - Wikipedia

    en.wikipedia.org/wiki/GLUT4

    The insulin signal transduction pathway begins when insulin binds to the insulin receptor proteins. Once the transduction pathway is completed, the GLUT-4 storage vesicles becomes one with the cellular membrane. As a result, the GLUT-4 protein channels become embedded into the membrane, allowing glucose to be transported into the cell.