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The removal of fluoroquinolones as a potential treatment left cephalosporins as the only viable antimicrobial option for gonorrhea treatment. Wary of further gonococcal resistance, the CDC's recommendations shifted in 2010 to a dual therapy strategy--cephalosporin with either azithromycin or doxycycline.
Treatment typically consists of cephalosporin and fluoroquinolone antibiotics. [4] Gonococcemia is typically treated with intravenous or intramuscular cephalosporin antibiotics. [ 5 ] Approximately 10-30% of gonorrheal infections present with a co-infection of chlamydia , so it is common to add a one-time dose of oral azithromycin or ...
Gonorrhoea or gonorrhea, colloquially known as the clap, [7] is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. [8] Infection may involve the genitals, mouth, or rectum. [9] Gonorrhea is spread through sexual contact with an infected person, [1] or from a mother to a child during birth. [1]
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics , a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s ...
Treatment cannot reverse any deformities, brain, or permanent tissue damage that has already occurred. [ 32 ] A Cochrane review found that antibiotics may be effective for serological cure but in general the evidence around the effectiveness of antibiotics for congenital syphilis is uncertain due to the poor methodological quality of the small ...
Common causes include infections due to gonorrhea, chlamydia, or trichomoniasis. [3] In gonorrhea the discharge may be white, yellow, or green. [4] [5] A swab of the discharge is usually performed. [5] Treatment depends on the cause. Spread of infection is reduced by also treating sexual contacts. [6]
Early diagnosis and immediate treatment are vital in reducing the chances of later complications from PID. Delaying treatment for even a few days could greatly increase the chances of further complications. Even when the PID infection is cured, effects of the infection may be permanent, or long lasting. This makes early identification essential.
Rates of reported gonorrhea have increased 111% since the historic low in 2009. During 2019–2020, the overall rate of reported gonorrhea increased 5.7%; rates increased among both males and females and in three regions of the United States (Midwest, Northeast, and South); rates of reported gonorrhea increased in 36 states and two US territories.