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  2. Famotidine - Wikipedia

    en.wikipedia.org/wiki/Famotidine

    Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger-Ellison syndrome . [ 4 ]

  3. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

  4. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

  5. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]

  6. Ibuprofen/famotidine - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen/famotidine

    Ibuprofen/famotidine, sold under the brand name Duexis, is a fixed-dose combination medication used for the treatment of rheumatoid arthritis and osteoarthritis. [1] It contains ibuprofen , a nonsteroidal anti-inflammatory drug (NSAID) and famotidine, a histamine H2-receptor antagonist .

  7. Bisoprolol - Wikipedia

    en.wikipedia.org/wiki/Bisoprolol

    Zebeta 5-mg oral tablet. Bisoprolol is used for prevention of cardiovascular events following a heart attack in patients with risk factors for disease progression, [16] in the management of congestive heart failure with reduced ejection fraction, [17] and as a second-line agent for hypertension.

  8. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    In a randomized, controlled trial 12 healthy volunteers ingested 200 mL of either grapefruit juice or water three times daily for five days. On the fourth day 10 mg of oxycodone hydrochloride were administered orally. Analgesic and behavioral effects were reported for 12 hours and plasma samples were analyzed for oxycodone metabolites for 48 hours.

  9. Lisuride - Wikipedia

    en.wikipedia.org/wiki/Lisuride

    Lisuride is a ligand of dopamine, serotonin, and adrenergic receptors as well as the histamine H 1 receptor. [4] It has sub-nanomolar affinity for the dopamine D 2, and D 3 receptors, serotonin 5-HT 1A and 5-HT 1D receptors, and α 2A-, α 2B-, and α 2C-adrenergic receptors, and low-nanomolar affinity for the dopamine D 1, D 4, and D 5 receptors, serotonin 5-HT 2A, 5-HT 2B, and 5-HT 2C ...

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