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  2. 2-Oxazolidinone - Wikipedia

    en.wikipedia.org/wiki/2-oxazolidinone

    Contezolid (MRX-I) has reported phase 1 data [12] and phase III data. [13] In 2021, a new drug summary was published by ADIS Press. [ 14 ] In June 2021, marketing approval was granted by the Chinese National Medical Products Administration (NMPA) for use of oral contezolid in moderate to severe complicated skin and skin structure infections. [ 15 ]

  3. Antimicrobial spectrum - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_spectrum

    The antimicrobial spectrum of an antibiotic can be determined by testing its antimicrobial activity against a wide range of microbes in vitro. Nonetheless, the range of microorganisms which an antibiotic can kill or inhibit in vivo may not always be the same as the antimicrobial spectrum based on data collected in vitro. [2] [5]

  4. Linezolid - Wikipedia

    en.wikipedia.org/wiki/Linezolid

    The oxazolidinone pharmacophore—the chemical "template" essential for antimicrobial activity—consists of a 1,3-oxazolidin-2-one moiety with an aryl group at position 3 and an S-methyl group, with another substituent attached to it, at position 5 (the R-enantiomers of all oxazolidinones are devoid of antibiotic properties). [108]

  5. Oxazolidinone - Wikipedia

    en.wikipedia.org/wiki/Oxazolidinone

    The oxazolidones and isoxazolidones are a set of six isomeric five-membered heterocyclic compounds consisting of a carbonyl group, an oxygen atom, a nitrogen atom with a hydrogen atom attached, and two methylene groups.

  6. Antibiotic sensitivity testing - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_sensitivity_testing

    [1] [9] The results of antimicrobial susceptibility tests performed during a given time period can be compiled, usually in the form of a table, to form an antibiogram. [31] [32] Antibiograms help the clinician to select the best empiric antimicrobial therapy based on the local resistance patterns until the laboratory test results are available ...

  7. Delpazolid - Wikipedia

    en.wikipedia.org/wiki/Delpazolid

    308.313 g·mol −1: 3D model : Interactive image; SMILES. ... Delpazolid (LCB01-0371) is an experimental antibiotic drug for the treatment of tuberculosis. [1] [2]

  8. McFarland standards - Wikipedia

    en.wikipedia.org/wiki/McFarland_standards

    A 0.5 McFarland standard is prepared by mixing 0.05 mL of 1.175% barium chloride dihydrate (BaCl 2 •2H 2 O), with 9.95 mL of 1% sulfuric acid (H 2 SO 4). [ 1 ] Now there are McFarland standards prepared from suspensions of latex particles, which lengthens the shelf life and stability of the suspensions.

  9. Oxazolidine - Wikipedia

    en.wikipedia.org/wiki/Oxazolidine

    Oxazolidine is a five-membered heterocycle ringwith the formula (CH 2) 3 (NH)O.The O atom and NH groups are not mutually bonded, in contrast to isoxazolidine. [2] [3] Oxazolidines (emphasis on plural) are derivatives of the parent oxazolidine owing to the presence of substituents on carbon and/or nitrogen.