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[9] [10] [11] In January 2012, Novo Nordisk was named the most sustainable company in the world by the business magazine Corporate Knights, while spin-off company Novozymes was named fourth. [12] It is a leader in the FTSE4Good Index, and the only European company in the top ten. [13] Novo Nordisk is the largest pharmaceutical company in ...
Insulin aspart, sold under the brand name NovoLog, among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [17] It is generally used by injection under the skin but may also be used by injection into a vein . [ 17 ]
Regular insulin can be made from the pancreas of pigs or cows. [2] Human versions can be made either by modifying pig versions or recombinant technology. [2] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [7] It is on the World Health Organization's List of Essential Medicines. [8]
Humulin was the first medication produced using modern genetic engineering techniques in which actual human DNA is inserted into a host cell (E. coli in this case). The host cells are then allowed to grow and reproduce normally, and due to the inserted human DNA, they produce a synthetic version of human insulin.
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Non-human insulins have caused allergic reactions in some patients related to the extent of purification, formation of non-neutralising antibodies is rarely observed with recombinant human insulin (insulin human rDNA) but allergy may occur in some patients. This may be enhanced by the preservatives used in insulin preparations, or occur as a ...
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In 1925, the brothers Harald and Thorvald Pedersen founded Novo Terapeutisk Laboratorium and Nordisk Insulinlaboratorium with the aim to produce insulin.In 1941 the company's predecessor launched its first enzyme, trypsin, extracted from the pancreas of animals and used to soften leather, and was the first to produce enzymes by fermentation using bacteria in the 1950s.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261