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Some rules of netiquette compiled into an emoji-like visual representation. Etiquette in technology, colloquially referred to as netiquette, is a term used to refer to the unofficial code of policies that encourage good behavior on the Internet which is used to regulate respect and polite behavior on social media platforms, online chatting sites, web forums, and other online engagement websites.
Polypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a splicing regulator, although it is also involved in alternative 3' end processing, mRNA stability and RNA localization. [ 1 ]
The perinucleolar compartment was first discovered due to characterizing the polypyrimidine tract-binding protein (PTB), which is an RNA binding protein involved with pre-mRNA splicing, stability, and regulating translation. [7] The PTB and other binding proteins are localized in the PNC to primarily process RNA polymerase II.
The PTB domains facilitate interaction with the activated tyrosine-phosphorylated insulin receptor. The PTB domain is situated towards the N terminus . Two arginines in this domain are responsible for hydrogen bonding phosphotyrosine residues on an Ac -LYASSNPApY- NH2 peptide in the juxtamembrane region of the insulin receptor.
Phosphotyrosine-binding domain (PTB): PTB domains usually bind to phosphorylated tyrosine residues. They are often found in signal transduction proteins. PTB-domain binding specificity is determined by residues to the amino-terminal side of the phosphotyrosine. Examples: the PTB domains of both SHC and IRS-1 bind to a NPXpY sequence.
The pygmy mammoth is an example of insular dwarfism, a case of Foster's rule, its unusually small body size an adaptation to the limited resources of its island home.. A biological rule or biological law is a generalized law, principle, or rule of thumb formulated to describe patterns observed in living organisms.
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There is a clear distinction between netizens and people who come online to use the internet. A netizen is described as an individual who actively seek to contribute to the development of the internet. [14] Netizens are not individuals who go online for personal gain or profit, but instead actively seeks to make the internet a better place. [15 ...