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Clearance of the drug is increased in children (age 1 to 12), teenagers (12 to 16), adult smokers, elderly smokers, as well as in cystic fibrosis, and hyperthyroidism. Clearance of the drug is decreased in these conditions: elderly, acute congestive heart failure, cirrhosis, hypothyroidism and febrile viral illnesses.
Senile pruritus is one of the most common conditions in the elderly or people over 65 years of age with an emerging itch that may be accompanied with changes in temperature and textural characteristics. [1] [2] [3] In the elderly, xerosis, is the most common cause for an itch due to the degradation of the skin barrier over time. [4]
A score of 6 or more indicates that there is a 50-75% probability of necrotizing fasciitis. A score of 8 or more represents over 75% likelihood of NF. [15] [19] [20] Patients with a LRINEC score ≥6 may have a higher rate of both death and amputation as well. [21] The scoring criteria are: [19] [22]
The legs and face are the most common sites involved, although cellulitis can occur on any part of the body. [1] The leg is typically affected following a break in the skin. [1] Other risk factors include obesity, leg swelling, and old age. [1] For facial infections, a break in the skin beforehand is not usually the case. [1]
Diabetic foot infection is any infection of the foot in a diabetic person. [2] The most frequent cause of hospitalization for diabetic patients is due to foot infections. [ 3 ] Symptoms may include pus from a wound, redness, swelling, pain, warmth, tachycardia , or tachypnea. [ 4 ]
Obese people tend to have raised levels of the hormone leptin, which is secreted by adipose tissue and under normal circumstances increases ventilation. In OHS, this effect is reduced. [5] [10] Furthermore, episodes of nighttime acidosis (e.g. due to sleep apnea) lead to compensation by the kidneys with retention of the alkali bicarbonate. This ...
It occurs in the lower legs, and is caused by excessive walking in hot temperatures. It is more common in elderly people. It is called golfer's vasculitis due to the walking involved in playing golf – a sport commonly practiced by older people. Disney rash became a name because the rash is common among visitors walking at Disney theme parks.
PLMD is estimated to occur in approximately 4% of adults (aged 15–100), [8] but is more common in the elderly, especially females, with up to 11% experiencing symptoms. [17] PLMD appears to be related to restless legs syndrome (RLS) - a study of 133 people found that 80% of those with RLS also had PLMS. [18]