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Bone mineral (also called inorganic bone phase, bone salt, or bone apatite) is the inorganic component of bone tissue. It gives bones their compressive strength . Bone mineral is formed predominantly from carbonated hydroxyapatite [ 1 ] [ 2 ] with lower crystallinity.
The resulting new bone is often called an involucrum. [13] On histologic examination, these areas of necrotic bone are the basis for distinguishing between acute osteomyelitis and chronic osteomyelitis. Osteomyelitis is an infective process that encompasses all of the bone (osseous) components, including the bone marrow.
Symptoms that patients may experience when bone disorders form can include bone deformities, hip pain, overgrowing of bone in an individual's skull which can result in headaches and a loss of hearing, pain and numbness in arm or legs if the spine is affected and an overall weakness in the body particularly in the hip and knee joints. [5]
Modified (flattened) osteoblasts become the lining cells that form a protective layer on the bone surface. The mineralised matrix of bone tissue has an organic component of mainly collagen called ossein and an inorganic component of bone mineral made up of various salts. Bone tissue is mineralized tissue of two types, cortical bone and ...
The classic symptoms of a bacterial infection are localized redness, heat, swelling and pain. One of the hallmarks of a bacterial infection is local pain, pain that is in a specific part of the body. For example, if a cut occurs and is infected with bacteria, pain occurs at the site of the infection.
In bone for example, the organic layer is the protein collagen. [3] The degree of mineral in mineralized tissues varies and the organic component occupies a smaller volume as tissue hardness increases. [1] [18] However, without this organic portion, the biological material would be brittle and break easily.
At a site of active bone resorption, the osteoclast forms a specialized cell membrane, the "ruffled border", that opposes the surface of the bone tissue. This extensively folded or ruffled border facilitates bone removal by dramatically increasing the cell surface for secretion and uptake of the resorption compartment contents and is a ...
Bacteria may secondarily colonize the socket, and lead to further dissolution of the clot. [5] Bacterial breakdown and fibrinolysis are widely accepted as major contributing factors to the loss of the clot. [5] Bone tissue is exposed to the oral environment, and a localized inflammatory reaction takes place in the adjacent marrow spaces. [4]