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Tizanidine is a derivative of 2,1,3-benzothiadiazole and its first published synthesis was reported in a patent. [17] The 5-chloro-2,1,3-benzothiadiazol-4-amine intermediate was a known compound, produced in three steps from 4-chlorophenylenediamine as shown. [ 18 ]
German submarine U-169 was a Type IXC/40 U-boat of Nazi Germany's Kriegsmarine built for service during World War II. Her keel was laid down on 15 May 1941 by the Deutsche Schiff- und Maschinenbau AG in Bremen as yard number 708. She was launched on 6 June 1942 and commissioned on 16 November with Oberleutnant zur See Hermann Bauer in command.
[medical citation needed] Elucidation of the exact mechanism of action is ongoing but there is limited study due to the existence of more effective, safe muscle relaxants (e.g., diazepam, cyclobenzaprine, tizanidine), greatly limiting the potential benefit of identifying novel compounds which share chlorzoxazone's mechanism of action.
The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in people who have not responded to at least two oral antidepressants.
A new review reports that nine people taking semaglutide and tirzepatide — the active ingredient in GLP-1 medications — experienced vision issues, including three potentially blinding eye ...
Breathing disorders are common in the U.S. with conditions like COPD affecting some 7% of the population and asthma affecting another 10%. Digestive conditions like GERD, ...
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8]
$169 at Walmart. Nordstrom. All-Clad HA1 Hard Anodized 3.5-Quart Nonstick Saucepan. $60 $100 Save $40. All-Clad is widely regarded as one of the best cookware brands out there today, and you can ...