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Glomerulonephrosis is a non-inflammatory disease of the kidney presenting primarily in the glomerulus (a glomerulopathy) as nephrotic syndrome.The nephron is the functional unit of the kidney and it contains the glomerulus, which acts as a filter for blood to retain proteins and blood lipids.
Nephrotic syndrome has many causes and may either be the result of a glomerular disease that can be either limited to the kidney, called primary nephrotic syndrome (primary glomerulonephrosis), or a condition that affects the kidney and other parts of the body, called secondary nephrotic syndrome.
Membranous glomerulonephritis (MGN) is a slowly progressive disease of the kidney affecting mostly people between ages of 30 and 50 years, usually white people (i.e., those of European, Middle Eastern, or North African ancestry.) [citation needed]. Video explanation
These presenting symptoms are relatively non-specific and are often seen in other glomerular disorders. Preceding upper respiratory tract infection or post-streptococcal glomerulonephritis may contribute to hematuria, as both have been identified in patients presenting with hematuria in the context of mesangial proliferative glomerulonephritis. [2]
Gastroesophageal reflux disease (return of the stomach’s contents into the esophagus, causing heartburn) Gastroparesis (slow emptying of the stomach) Small bowel intestinal bacterial overgrowth
Aggressive Berger's disease (a rarer form of the disease) can attack other major organs, such as the liver, skin and heart. IgA nephropathy is the most common glomerulonephritis worldwide; the global incidence is 2.5/100,000 per year amongst adults. [1] Aggressive Berger's disease is on the NORD list of rare diseases. [2]
Glomerulocystic kidney disease (GCKD) is a renal cystic disease that can be classified in five major groups [3] including familial, familial/sporadic heritable, glomerulocystic kidneys as a component of other cystic disease, sporadic, and acquired.
Underlying causes for glomerular injury can be inflammatory, toxic or metabolic. [8] These can be seen in the urine ( urinalysis ) on microscopic and chemical (dipstick) examination. Glomerular diseases include diabetic kidney disease , glomerulonephritis (inflammation), glomerulosclerosis (hardening of the glomeruli), and IgA nephropathy .