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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
every day / daily quaque die q.h.s., qhs every night at bedtime quaque hora somni q.d.s, qds, QDS 4 times a day quater die sumendum q.i.d, qid 4 times a day quater in die q.h., qh every hour, hourly quaque hora q.o.d., qod every other day / alternate days quaque altera die q.p.m., qPM, qpm every afternoon or evening: quaque post meridiem q.s., qs
Cholinesterase inhibition was observed at all dose levels tested, and a NOAEL of 0.03 mg/kg/day estimated by dividing a LOAEL of 0.3 mg/kg/day by an uncertainty factor of 10. As with the acute RfD, the chronic RfD of 3×10 −4 mg/kg/day was determined by dividing this NOAEL by the inter- and intraspecies uncertainty factors.
For the drugs administered by oral and dermal route, the units of threshold dose are mg/kg body-weight/day (dose of the drug in mg per body weight in kg per day) or ppm (parts per million), while the threshold dose of drugs by inhalation delivery has the unit of mg/L 6h/day (amount of drug in mg in 1L of air, for 6 hours per day). [8]
o can be mistaken as an a which could read "a.s.", meaning left ear o.u. oculus uterque: both eyes o can be mistaken as an a which could read "a.u.", meaning both ears oz ounce p. perstetur: continue part. æq. partes æquales: equal parts per: per: by or through p.c. post cibum: after meals p.c.h.s., pc&hs post cibum et hora somni: after meals ...
The result is expressed in mg/kg body mass. Dermal Toxicity : LD 50 for acute dermal toxicity means that dose of the material which, administered by continuous contact for 24 hours with the shaved intact skin (avoiding abrading) of an albino rabbit, causes death within 14 days in half of the animals tested.
The JECFA makes a distinction between acceptable intakes and tolerable intakes. Tolerable is used to demonstrate permissibility, not acceptability. [3] Substances such as food additives, veterinary drugs, and pesticides that can be controlled in the food supply relatively easily are assessed an acceptable daily intake, or ADI.
twice a day (from Latin bis in die) BDD: body dysmorphic disorder: BDI: Beck Depression Inventory: BDS: two times a day (from Latin bis die sumendus) BE: barium enema base excess: BEAM: A type of high-dose chemotherapy used to treat lymphoma prior to a stem cell transplant BEP: bleomycin, etoposide, and cisplatin (chemotherapy regimen) BF ...