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The most detailed study to date conducted in aging male mice reveals some of the mechanisms through which a ketogenic diet may help protect the aging brain. How keto diets may help boost memory ...
A study showed that infusing the nourishing cerebrospinal fluid from around brain cells of young mice into aged brains rejuvenates aspects of the brain, proving that it play a role in brain aging and inter alia identifying a protein FGF17 as a key target for potential therapeutics, including for anti-aging.
Each macronutrient can impact cognition through multiple mechanisms, including glucose and insulin metabolism, neurotransmitter actions, oxidative stress and inflammation, and the gut-brain axis. [4] [5] [6] Inadequate macronutrient consumption or proportion could impair optimal cognitive functioning and have long-term health implications.
“Following a healthy lifestyle is good for the brain,” says Amit Sachdev, M.D., M.S., medical director in the Department of Neurology at Michigan State University.
Ketosis is a metabolic state characterized by elevated levels of ketone bodies in the blood or urine. Physiological ketosis is a normal response to low glucose availability. In physiological ketosis, ketones in the blood are elevated above baseline levels, but the body's acid–base homeostasis is maintained.
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The ketogenic diet is a high-fat, adequate-protein, low-carbohydrate dietary therapy that in conventional medicine is used mainly to treat hard-to-control (refractory) epilepsy in children. The diet forces the body to burn fats rather than carbohydrates.
This is an accepted version of this page This is the latest accepted revision, reviewed on 18 February 2025. Diets restricting carbohydrate consumption This article is about low-carbohydrate dieting as a lifestyle choice or for weight loss. For information on low-carbohydrate dieting as a therapy for epilepsy, see Ketogenic diet. An example of a low-carbohydrate dish, cooked kale and poached ...