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Insomnia can be grouped into primary and secondary, or comorbid, insomnia. [124] [125] [126] Primary insomnia is a sleep disorder not attributable to a medical, psychiatric, or environmental cause. [127] There are three main types of primary insomnia.
Taurine (/ ˈ t ɔː r iː n /), or 2-aminoethanesulfonic acid, is a non-proteinogenic naturally occurring amino sulfonic acid that is widely distributed in animal tissues. [1] It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight.
Tyramine is considered a "false neurotransmitter", as it enters noradrenergic nerve terminals and displaces large amounts of norepinephrine, which enters the blood stream and causes vasoconstriction. Additionally, cocaine has been found to block blood pressure rise that is originally attributed to tyramine, which is explained by the blocking of ...
There's a vicious cycle whereby IBS can cause insomnia and disrupt your ability to get quality sleep, only to make the abdominal symptoms and related anxiety and tiredness worse the next day ...
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Insomnia can occur independently or as a result of another problem. [2] Conditions that can result in insomnia include psychological stress, chronic pain, heart failure, hyperthyroidism, heartburn, restless leg syndrome, menopause, certain medications, and drugs such as caffeine, nicotine, and alcohol.
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The two receptors GABA-α and GABA-ρ are ion channels ...
Agomelatine does not alter daytime vigilance and memory in healthy volunteers. In depressed patients, treatment with the drug increased slow-wave sleep without modification of REM (rapid eye movement) sleep amount or REM latency. [28] Agomelatine also induced an advance of the time of sleep onset and of minimum heart rate.
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