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The use of gold compounds has decreased since the 1980s because of numerous side effects and monitoring requirements, limited efficacy, and very slow onset of action. Most chemical compounds of gold, including some of the drugs discussed below, are not salts, but are examples of metal thiolate complexes .
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Most drugs based on gold are Au(I) derivatives. [3] Au(III) (referred to as the auric) is a common oxidation state, and is illustrated by gold(III) chloride, Au 2 Cl 6. The gold atom centers in Au(III) complexes, like other d 8 compounds, are typically square planar, with chemical bonds that have both covalent and ionic character.
Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. [ 2 ] [ 3 ] Along with an orally-administered gold salt, auranofin , it is one of only two gold compounds currently employed in modern medicine.
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Category: Gold compounds. 40 languages. ... Template:Gold compounds This page was last edited on 4 January 2024, at 11:49 (UTC). Text is available under the ...
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Template: III-V compounds. ... III refers to the boron group (the table columns). V refers to the nitrogen group (the table rows). III-V compounds (binary) 5 B: 13 Al ...