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Mycobacterium ulcerans is a species of bacteria found in various aquatic environments. The bacteria can infect humans and some other animals, causing persistent open wounds called Buruli ulcer . M. ulcerans is closely related to Mycobacterium marinum , from which it evolved around one million years ago, and more distantly to the mycobacteria ...
M. ulcerans is a mycobacterium, closely related to Mycobacterium marinum which infects aquatic animals and, rarely, humans. [9] It is more distantly related to other slow-growing mycobacteria that infect humans, such as Mycobacterium tuberculosis , which causes tuberculosis , and Mycobacterium leprae , which causes leprosy . [ 10 ]
There is now considerable evidence to suggest that this disease is an infection. Mycobacterium ulcerans has recently been isolated from lesions and is unique to tropical ulcers. [5] Early lesions may be colonized or infected by, Bacillus fusiformis (Vincent's organism), anaerobes and spirochaetes.
Mycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae.This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (M. tuberculosis) and leprosy in humans.
Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenic mycobacteria species including M. ulcerans, M. liflandii (an unofficial designation), M. pseudoshottsii, and some strains of M. marinum. These mycobacteria are collectively referred to as mycolactone-producing mycobacteria or MPM ...
Runyon III organisms (nonchromogens) are slow-growing and never produce pigment, regardless of culture conditions. The group includes Mycobacterium avium and Mycobacterium intracellulare (together known as the MAC complex), Mycobacterium tuberculosis, Mycobacterium ulcerans and numerous other organisms. Mycobacterium xenopi is also a nonchromogen.
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
The disease has a high curability. [17] Soft-tissue disease due to NTM infection include post-traumatic abscesses (caused by rapid growers), swimming pool granuloma (caused by M. marinum) and Buruli ulcer (caused by M. ulcerans or M. shinshuense). Post-traumatic abscesses most commonly occur after injection. [17]