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The use of gold compounds has decreased since the 1980s because of numerous side effects and monitoring requirements, limited efficacy, and very slow onset of action. Most chemical compounds of gold, including some of the drugs discussed below, are not salts, but are examples of metal thiolate complexes .
Most drugs based on gold are Au(I) derivatives. [3] Au(III) (referred to as the auric) is a common oxidation state, and is illustrated by gold(III) chloride, Au 2 Cl 6. The gold atom centers in Au(III) complexes, like other d 8 compounds, are typically square planar, with chemical bonds that have both covalent and ionic character.
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Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. [ 2 ] [ 3 ] Along with an orally-administered gold salt, auranofin , it is one of only two gold compounds currently employed in modern medicine.
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A typical housie/Bingo ticket. In UK bingo, or Housie, cards are usually called "tickets." The cards contain three rows and nine columns. Each row contains five numbers and four blank spaces randomly distributed along the row. Numbers are apportioned by column (1–9, 10–19, 20–29, 30–39, 40–49, 50–59, 60–69, 70–79 and 80–90). [9]
The highest scoring 7-letter bingo is "MUZJIKS". Though the sum total of the seven tiles is 29 points, if the Z is placed on the double letter square (for maximum score value), the resulting score is (39x2) + 50 = 128 points. The highest scoring 8-letter bingo in Collins is "QUIZZIFY" (using a blank for one of the Zs). Placed on two triple-word ...
Nitratoauric acid, hydrogen tetranitratoaurate, or simply called gold(III) nitrate is a crystalline gold compound that forms the trihydrate, HAu(NO 3) 4 ·3H 2 O or more correctly H 5 O 2 Au(NO 3) 4 ·H 2 O. [3] [2] This compound is an intermediate in the process of extracting gold. [4] In older literature it is also known as aurinitric acid. [5]