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The necessity of such a system is demonstrated by what happens when the system breaks down, as seen when advanced hepatic fibrosis in cirrhosis leads to hepatic encephalopathy in the brain owing to the blood being loaded with ammonia and other substances not conducive to brain function. Blood flow to the liver is unique in that it receives both ...
The liver receives a dual blood supply from the hepatic portal vein and hepatic arteries. The hepatic portal vein delivers around 75% of the liver's blood supply and carries venous blood drained from the spleen, gastrointestinal tract, and its associated organs. The hepatic arteries supply arterial blood to the liver, accounting for the ...
An experiment from Harvey's Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus. Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus (Latin, 'An Anatomical Exercise on the Motion of the Heart and Blood in Living Beings'), commonly called De Motu Cordis, is the best-known work of the physician William Harvey, which was first published in 1628 and established the ...
The "little brain in the heart" is an intricate system of nerve cells that control and regulate the heart's activity. It is also called the intrinsic cardiac nervous system (ICNS). [15] It consists of about 40,000 neurons that form clusters or ganglia around the heart, especially near the top where the blood vessels enter and exit.
All plasma proteins except Gamma-globulins are synthesised in the liver. [1] Human serum albumin, osmolyte and carrier protein; α-fetoprotein, the fetal counterpart of serum albumin; Soluble plasma fibronectin, forming a blood clot that stops bleeding; C-reactive protein, opsonin on microbes, [2] acute phase protein; Various other globulins
Hilum of the liver. In human anatomy, the hilum (/ ˈ h aɪ l ə m /; pl.: hila), sometimes formerly called a hilus (/ ˈ h aɪ l ə s /; pl.: hili), is a depression or fissure where structures such as blood vessels and nerves enter an organ. Examples include: Hilum of kidney, admits the renal artery, vein, ureter, and nerves
The periportal space (Latin: spatium periportale), or periportal space of Mall, [9] is a space between the stroma of the portal canal and the outermost hepatocytes in the hepatic lobule, and is thought to be one of the sites where lymph originates in the liver. [10] Fluid (residual blood plasma) that is not taken up by hepatocytes drains into ...
Ischemic hepatitis, also known as shock liver, is a condition defined as an acute liver injury caused by insufficient blood flow (and consequently insufficient oxygen delivery) to the liver. [5] The decreased blood flow to the liver is usually due to shock or low blood pressure. However, local causes involving the hepatic artery that supplies ...